Invokana is an example of which drug class?

Invokana is an example of which drug class?

• A. DPP-4 inhibitor
• B. GLP-1 receptor agonist
• C. SGLT-2 inhibitors
• D. Serotonin receptor antagonist

Answer: (C)

Invokana belongs to the SGLT-2 inhibitors. It works by blocking the sodium-glucose cotransporter 2 in the kidney’s proximal tubule, which reduces reabsorption of filtered glucose and increases glucose excretion in the urine. This mechanism lowers blood sugar in people with type 2 diabetes and defines the SGLT-2 inhibitor class (often called gliflozins). Other option classes use different action pathways—DPP-4 inhibitors boost incretin hormones to raise insulin and lower glucagon, GLP-1 receptor agonists mimic incretin to enhance insulin secretion, and serotonin receptor antagonists act on serotonin pathways for other indications. So Invokana is correctly categorized as an SGLT-2 inhibitor.