Phentermine and Diethylpropion are contraindicated in patients with which history?

Phentermine and Diethylpropion are contraindicated in patients with which history?

• A. Hyperlipidemia
• B. History of cardiovascular disease
• C. Asthma
• D. Controlled hypertension

Answer: (B)

These drugs are stimulant appetite suppressants that increase sympathetic activity, which raises heart rate and blood pressure. Because they put extra strain on the heart, they are avoided in people with cardiovascular disease. A history of cardiovascular disease signals existing heart or blood vessel problems, and using these medications could worsen conditions such as angina, arrhythmias, or heart failure. That safety concern is why a history of cardiovascular disease is the contraindication. Hyperlipidemia and asthma don’t directly create the cardiac risk these stimulants pose, and while hypertension can be a consideration, the strongest and most direct contraindication among the options is a history of cardiovascular disease.

These drugs are stimulant appetite suppressants that increase sympathetic activity, which raises heart rate and blood pressure. Because they put extra strain on the heart, they are avoided in people with cardiovascular disease. A history of cardiovascular disease signals existing heart or blood vessel problems, and using these medications could worsen conditions such as angina, arrhythmias, or heart failure. That safety concern is why a history of cardiovascular disease is the contraindication.

Hyperlipidemia and asthma don’t directly create the cardiac risk these stimulants pose, and while hypertension can be a consideration, the strongest and most direct contraindication among the options is a history of cardiovascular disease.