Which option is listed for post-operative weight regain management?

Which option is listed for post-operative weight regain management?

• A. Lifestyle intervention + Liraglutide OR phentermine/topiramate
• B. Metformin only
• C. Orlistat only
• D. Lorcaserin only

Answer: (A)

Post-operative weight regain is best managed by reinforcing lifestyle changes and adding a weight-loss medication when needed. The combination of sustained lifestyle intervention with an anti-obesity medication gives the most evidence-based path to help patients reduce regain after bariatric surgery. Liraglutide, a GLP-1 receptor agonist, and phentermine/topiramate (Qsymia) are both proven options to support further weight loss when used alongside diet and exercise, making this pairing the strongest choice for managing regain. Metformin alone isn’t a primary weight-loss strategy after surgery, and orlistat offers only modest weight loss and isn’t a standard post-op approach. Lorcaserin was removed from the market over safety concerns, so it isn’t a viable option.

Post-operative weight regain is best managed by reinforcing lifestyle changes and adding a weight-loss medication when needed. The combination of sustained lifestyle intervention with an anti-obesity medication gives the most evidence-based path to help patients reduce regain after bariatric surgery. Liraglutide, a GLP-1 receptor agonist, and phentermine/topiramate (Qsymia) are both proven options to support further weight loss when used alongside diet and exercise, making this pairing the strongest choice for managing regain.

Metformin alone isn’t a primary weight-loss strategy after surgery, and orlistat offers only modest weight loss and isn’t a standard post-op approach. Lorcaserin was removed from the market over safety concerns, so it isn’t a viable option.